PUBLICATIONS


GUIDELINES

Affiliations


Laboratory of Excellence GR-Ex ou Laboratoire d’Excellence GR-Ex.

Funding


This study was supported by grants from Laboratory of Excellence GR-Ex, reference ANR-11-LABX-0051. The labex GR-Ex is funded by the program “Investissements d’avenir” of the French National Research Agency, reference ANR-11-IDEX-0005-02.

Acknowledgments


Name } was supported by a labex GR-Ex fellowship and/or scholarship. The labex GR-Ex, reference ANR-11-LABX-0051 is funded by the program “Investissements d’avenir” of the French National Research Agency, reference ANR-11-IDEX-0005-02.

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Charlot, Keyne; Romana, Marc; Moeckesch, Berenike; Jumet, Stí©phane; Waltz, Xavier; Divialle-Doumdo, Lydia; Hardy-Dessources, Marie-Dominique; Petras, Marie; TressiíÂres, Benoí¬t; Tarer, Vanessa; Hue, Olivier; Etienne-Julan, Maryse; Antoine-Jonville, Sophie; Connes, PhilippeWhich side of the balance determines the frequency of vaso-occlusive crises in children with sickle cell anemia: Blood viscosity or microvascular dysfunction?Blood Cells, Molecules & Diseases2016
Deschemin, Jean-Christophe; Noordine, Marie-Louise; Remot, Aude; Willemetz, Alexandra; Afif, Clí©ment; Canonne-Hergaux, Franí_ois; Langella, Philippe; Karim, Zoubida; Vaulont, Sophie; Thomas, Muriel; Nicolas, Gaí‚lThe microbiota shifts the iron sensing of intestinal cellsFASEB journal2016
Chirico, Erica N.; Fa‘s, Camille; Connes, Philippe; Canet-Soulas, Emmanuelle; Martin, Cyril; Pialoux, VincentRole of Exercise-Induced Oxidative Stress in Sickle Cell Trait and DiseaseSports Medicine2016
de Brevern, Alexandre G.Extension of the classical classification of _-turnsScientific Reports2016
Roelens, Marie; Dossier, Claire; Fenneteau, Odile; Couque, Nathalie; Da Costa, LydieGlucose-6-phosphate dehydrogenase deficiency: the added value of cytologyAnnales De Biologie Clinique2016
Daher, Raed; Kannengiesser, Caroline; Houamel, Dounia; Lefebvre, Thibaud; Bardou-Jacquet, Edouard; Ducrot, Nicolas; de Kerguenec, Caroline; Jouanolle, Anne-Marie; Robreau, Anne-Marie; Oudin, Claire; Le Gac, Gerald; Moulouel, Boualem; Loustaud-Ratti, Veronique; Bedossa, Pierre; Valla, Dominique; Gouya, Laurent; Beaumont, Carole; Brissot, Pierre; Puy, Herví©; Karim, Zoubida; Tchernitchko, DimitriHeterozygous Mutations in BMP6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in HumansGastroenterology2016
DiakitŽ, Seidina A. S.; Ndour, Papa Alioune; Brousse, Valentine; Gay, Frederick; Roussel, Camille; Biligui, Sylvestre; Dussiot, Michaí‚l; Prendki, Virginie; Lopera-Mesa, Tatiana M.; Traorí©, Karim; Konatí©, Drissa; Doumbia, Saibou; Cros, Jí©ríÇme; Dokmak, Safi; Fairhurst, Rick M.; Diakití©, Mahamadou; Buffet, Pierre A.Stage-dependent fate of Plasmodium falciparum-infected red blood cells in the spleen and sickle-cell trait-related protection against malariaMalaria Journal2016
Anheim, Mathieu; Lopez-Sanchez, Uriel; Giovannini, Donatella; Richard, Anne-Claire; Touhami, Jawida; N'Guyen, Ludovic; Rudolf, Gabrielle; Thibault-Stoll, Anne; Frebourg, Thierry; Hannequin, Didier; Campion, Dominique; Battini, Jean-Luc; Sitbon, Marc; Nicolas, Ga‘lXPR1 mutations are a rare cause of primary familial brain calcificationJournal of Neurology2016
Postic, Guillaume; Ghouzam, Yassine; Guiraud, Vincent; Gelly, Jean-ChristopheMembrane positioning for high- and low-resolution protein structures through a binary classification approachProtein engineering, design & selection2016
Cita, Kizzy-Clara; Brureau, Laurent; Lemonne, Nathalie; Billaud, Marie; Connes, Philippe; Ferdinand, SŽverine; Tressires, Benoit; Tarer, Vanessa; Etienne-Julan, Maryse; Blanchet, Pascal; Elion, Jacques; Romana, MarcMen with Sickle Cell Anemia and Priapism Exhibit Increased Hemolytic Rate, Decreased Red Blood Cell Deformability and Increased Red Blood Cell Aggregate StrengthPloS One2016
Sommet, Julie; Alberti, Corinne; Couque, Nathalie; Verlhac, Suzanne; Haouari, Zinedine; Mohamed, Damir; Franí_ois, Martine; Missud, Florence; Holvoet, Laurent; Elmaleh, Monique; Ithier, Ghislaine; Denjean, Andrí©; Elion, Jacques; Baruchel, Andrí©; Benkerrou, MalikaClinical and haematological risk factors for cerebral macrovasculopathy in a sickle cell disease newborn cohort: a prospective studyBritish Journal of Haematology2016
Mozar, Ana•s; Connes, Philippe; Collins, Bianca; Hardy-Dessources, Marie-Dominique; Romana, Marc; Lemonne, Nathalie; Bloch, Wilhelm; Grau, MarijkeRed blood cell nitric oxide synthase modulates red blood cell deformabilityin sickle cell anemiaClinical Hemorheology and Microcirculation2016
Giger, Katie; Habib, Ibrahim; Ritchie, Ken; Low, Philip S.Diffusion of glycophorin A in human erythrocytesBiochimica Et Biophysica Acta2016
Chadebech, Philippe; de MŽnorval, Marie-AmŽlie; Bodivit, Gwellaouen; Mekontso-Dessap, Armand; Pakdaman, Sadaf; Jouard, Alicia; GalactŽros, FrŽdŽric; Bierling, Philippe; Habibi, Anoosha; Pirenne, FranceEvidence of benefits from using fresh and cryopreserved blood to transfuse patients with acute sickle cell diseaseTransfusion2016
Postic, Guillaume; Ghouzam, Yassine; Gelly, Jean-ChristopheOREMPRO web server: orientation and assessment of atomistic and coarse-grained structures of membrane proteinsBioinformatics2016
de Moraes, Luciana V.; Dechavanne, Sebastien; Sousa, Patricia M.; Barateiro, AndrŽ; Cunha, Sonia F.; Nunes-Silva, Sofia; Lima, Flavia A.; Murillo, Oscar; Marinho, Claudio R. F.; Gangnard, Stephane; Srivastava, Anand; Braks, Joanna A.; Janse, Chris J.; Gamain, Benoit; Franke-Fayard, Blandine; Penha-Gonalves, CarlosMurine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in PregnancyInfection and Immunity2016
Bandje, Kossiwa; Naissant, Bernina; Bigey, Pascal; Lohezic, Murielle; Vayssires, Marlne; Blaud, Magali; Kermasson, Laetitia; Lopez-Rubio, JosŽ-Juan; Langsley, Gordon; Lavazec, Catherine; Deloron, Philippe; Merckx, Ana•sCharacterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparumMalaria Journal2016
Sandor, Barbara; Marin, Micka‘l; Lapoumeroulie, Claudine; Raba•, Miklos; Lefevre, Sophie D.; Lemonne, Nathalie; El Nemer, Wassim; Mozar, Ana•s; Franais, Olivier; Le Pioufle, Bruno; Connes, Philippe; Le Van Kim, CarolineEffects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemiaBritish Journal of Haematology2016
Tchernitchko, Dimitri; Scotet, Virginie; Lefebvre, Thibaud; L'Hostis, Carine; Gourlaouen, Isabelle; Merour, Marie-Christine; Rebah, Khadidja; Peoc'h, Katell; Assari, Suzanne; Ferec, Claude; Puy, HervŽ; Gac, GŽrald LeGNPAT polymorphism rs11558492 is not associated with increased severity in a large cohort of HFE p.Cys282Tyr homozygous patientsHepatology2016
Houamel, Dounia; Ducrot, Nicolas; Lefebvre, Thibaud; Daher, Raed; Moulouel, Boualem; Sari, Marie-Agnes; Letteron, Philippe; Lyoumi, Said; Millot, Sarah; Tourret, Jerome; Bouvet, Odile; Vaulont, Sophie; Vandewalle, Alain; Denamur, Erick; Puy, HervŽ; Beaumont, Carole; Gouya, Laurent; Karim, ZoubidaHepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coliJournal of the American Society of Nephrology2016
Khalyfa, Abdelnaby; Khalyfa, Ahamed A.; Akbarpour, Mahzad; Connes, Phillippe; Romana, Marc; Lapping-Carr, Gabrielle; Zhang, Chunling; Andrade, Jorge; Gozal, DavidExtracellular microvesicle microRNAs in children with sickle cell anaemia with divergent clinical phenotypesBritish Journal of Haematology2016
Cita, Kizzy-Clara; Ferdinand, SŽverine; Connes, Philippe; Brudey, Laura; Tressires, Benoit; Etienne-Julan, Maryse; Lemonne, Nathalie; Tarer, Vanessa; Elion, Jacques; Romana, MarcAssociation of adenylyl cyclase 6 rs3730070 polymorphism and hemolytic level in patients with sickle cell anemiaBlood Cells, Molecules & Diseases2016
Singh, Amrathlal Rabbind; Lacan, Philippe; Cadet, Estelle; Bignet, Patricia; Dumesnil, Cí©cile; Vannier, Jean-Pierre; Joly, Philippe; Rochette, JacquesA New Intergenic _-Globin Deletion (_-__125) Found in a Kabyle PopulationHemoglobin2016
Renoux, CŽline; Romana, Marc; Joly, Philippe; Ferdinand, Sí©verine; Faes, Camille; Lemonne, Nathalie; Skinner, Sarah; Garnier, Nathalie; Etienne-Julan, Maryse; Bertrand, Yves; Petras, Marie; Cannas, Giovanna; Divialle-Doumdo, Lydia; Nader, Elie; Cuzzubbo, Daniela; Lamarre, Yann; Gauthier, Alexandra; Waltz, Xavier; Kebaili, Kamila; Martin, Cyril; Hot, Arnaud; Hardy-Dessources, Marie-Dominique; Pialoux, Vincent; Connes, PhilippeEffect of Age on Blood Rheology in Sickle Cell Anaemia and Sickle Cell Haemoglobin C Disease: A Cross-Sectional StudyPloS One2016
Marginedas-Freixa, I.; Hattab, C.; Bouyer, G.; Halle, F.; Chene, A.; Lefevre, S. D.; Cambot, M.; Cueff, A.; Schmitt, M.; Gamain, B.; Lacapere, J. J.; Egee, S.; Bihel, F.; Le Van Kim, C.; Ostuni, M. A.TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human bloodScientific Reports2016
Mahfoudhi, Emna; Lordier, Larissa; Marty, Caroline; Pan, Jiajia; Roy, Anita; Roy, Lydia; Rameau, Philippe; Abbes, Salem; Debili, Najet; Raslova, Hana; Chang, Yunhua; Debussche, Laurent; Vainchenker, William; Plo, IsabelleP53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesisOncotarget2016
de Bataille, S.; Dutartre, H.; Puy, H.; Deybach, J.-C.; Gouya, L.; Raffray, E.; Pithon, M.; Stalder, J.-F.; Nguyen, J.-M.; Barbarot, S.Influence of meteorological data on sun tolerance in patients with erythropoietic protoporphyria in FranceThe British Journal of Dermatology2016
Renoux, CŽline; Parrow, Nermi; Faes, Camille; Joly, Philippe; Hardeman, Max; Tisdale, John; Levine, Mark; Garnier, Nathalie; Bertrand, Yves; Kebaili, Kamila; Cuzzubbo, Daniela; Cannas, Giovanna; Martin, Cyril; Connes, PhilippeImportance of methodological standardization for the ektacytometric measures of red blood cell deformability in sickle cell anemiaClinical Hemorheology and Microcirculation2016
Etoka-Beka, Mandingha Kosso; Ntoumi, Francine; Kombo, Michael; Deibert, Julia; Poulain, Pierre; Vouvoungui, Christevy; Kobawila, Simon Charles; Koukouikila-Koussounda, FelixPlasmodium falciparum infection in febrile Congolese children: prevalence of clinical malaria ten years after introduction of artemisinin-combination therapiesTropical medicine & international health2016
Arlet, Jean-Beno”t; Guillem, Flavia; Lamarque, Mathilde; Dussiot, Michael; Maciel, Thiago; Moura, Ivan; Hermine, Olivier; Courtois, GeneviveProtein-based therapeutic for anemia caused by dyserythropoiesisExpert Review of Proteomics2016
Noel, Floriane; Malpertuy, Alain; de Brevern, Alexandre G.Global analysis of VHHs framework regions with a structural alphabetBiochimie2016
Palazzo, Alberta; Bluteau, Olivier; Messaoudi, Kahia; Marangoni, Francesco; Chang, Yunhua; Souquere, Sylvie; Pierron, Gí©rard; Lapierre, ValŽrie; Zheng, Yi; Vainchenker, William; Raslova, Hana; Debili, NajetThe cell division control protein 42 /Src family kinase/Neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formationJournal of thrombosis and haemostasis2016
Da Costa, Lydie; Suner, Ludovic; Galimand, Julie; Bonnel, Amandine; Pascreau, Tiffany; Couque, Nathalie; Fenneteau, Odile; Mohandas, Narla; Society of Hematology and Pediatric Immunology (SHIP) group; French Society of Hematology (SFH)Diagnostic tool for red blood cell membrane disorders: Assessment of a new generation ektacytometerBlood Cells, Molecules & Diseases2016
Lasocki, Sigismond; Piednoir, Pascale; Couffignal, Camille; Rineau, Emmanuel; Dufour, Guillaume; Lefebvre, Thibaud; Puy, Herve; Duval, Xavier; Driss, Fathi; Schilte, ClementineDoes IV Iron Induce Plasma Oxidative Stress in Critically Ill Patients? A Comparison With Healthy VolunteersCritical Care Medicine2016
Kalaivani, Raju; de Brevern, Alexandre G.; Srinivasan, NarayanaswamyConservation of structural fluctuations in homologous protein kinases and its implications on functional sitesProteins2016
Ibanez, Clara; Habibi, Anoosha; Mekontso-Dessap, Armand; Chadebech, Philippe; Chami, Btissam; Bierling, Philippe; GalactŽros, FrŽdŽric; Rieux, Claire; Nataf, Jo‘lle; Bartolucci, Pablo; Peyrard, Thierry; Pirenne, FranceAnti-HI can cause a severe delayed hemolytic transfusion reaction with hyperhemolysis in sickle cell disease patientsTransfusion2016
Bartolucci, Pablo; Habibi, Anoosha; StehlŽ, Thomas; Di Liberto, Gaetana; Rakotoson, Marie Georgine; Gellen-Dautremer, Justine; Loric, Sylvain; Moutereau, StŽphane; Sahali, Dil; Wagner-Ballon, Orianne; Remy, Philippe; Lang, Philippe; Grimbert, Philippe; Audureau, Etienne; Godeau, Bertrand; Galacteros, Frédéric; Audard, VincentSix Months of Hydroxyurea Reduces Albuminuria in Patients with Sickle Cell DiseaseJournal of the American Society of Nephrology2016
Emilie-Fleur, Gautier; Sarah, Ducamp; Marjorie, Leduc; Virginie, Salnot; François, Guillonneau; Michael, Dussiot; John, Hale; Marie-Catherine, Giarratana; Anna, Raimbault; Luc, Douay; Catherine, Lacombe; Narla, Mohandas; Frédérique, Verdier; Yael, Zermati; Patrick, MayeuxComprehensive Proteomic Analysis of Human ErythropoiesisCell Reports2016
Nelly, Reihani; Jean-Benoit, Arlet; Michael, Dussiot; Thierry Billette, de Villemeur; Nadia, Belmatoug; Christian, Rose; Yves, Colin-Aronovicz; Olivier, Hermine; Caroline, Le Van Kim; Melanie, FrancoUnexpected macrophage-independent dyserythropoiesis in Gaucher diseaseHaematologica2016
Ware, Russell E; de Montalembert, Mariane; Tsilolo, Léon; Abboud, Miguel RSickle cell diseaseThe lancet2017
Renoux, Céline; Connes, Philippe et al.Alpha-thalassaemia promotes frequent vaso-occlusive crises in children with sickle cell anaemia through haemorheological changesPediatr Blood Cancer2017
Lefèvre, Carine; Bondu, Sabrina; Kosmider, Olivier; Michaela, FontenayDyserythropoiesis of myelodysplastic syndromes.Current Opinion in Hematology2017
Orvain, Corentin; Joly, Philippe et al.Diagnostic approach to hemoglobins with high oxygen affinity: experience from France and Belgium and review of the literatureAnnales de Biologie Clinique2017
Joly, Philippe; Renoux, Céline et al.UGT1A1 (TA)n genotype is not the major risk factor of cholelithiasis in sickle cell disease childrenEuropean Journal of Haematology2017
Roussel, Camille; Dussiot, Michael; Marin, Mickael; Morel, Alexandre; Ndour, Papa Alioune; Duez, Julien; Le Van Kim, Caroline; Hermine, Olivier; Colin, Yves; Buffet, Pierre; Amireault, Pascal Spherocytic shift of red blood cells during storage provides a quantitative whole cell-based marker of the storage lesionTransfusion2017
Narwani, Tarun Jairaj; Santuz, Hubert; Shinada, Nicolas; Melarkode Vatterkatte, Akhila; Ghouzam, Yassine; Srinivasan, Narayanasamy; Gelly, Jean-Christophe; de Brevern, Alexandre G.Recent advances on polyproline IIAmino Acids2017
Duffier, Yoann; Lavazec, Catherine et al.A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugsScientific Reports2016
Hierso, Régine; Hardy-Dessources, Marie-Dominique et al.Exacerbation of oxidative stress during sickle vaso-occlusive crisis is associated with decreased anti-band 3 autoantibodies rate and increased red blood cell-derived microparticle level: a prospective studyBr. J. Haematol.2017